Tuesday
April 10
15:00 – 17:00 Registration
17:00 – 17:45 Keynote Lecture 1
Leslie Vosshall (USA)
The Genetics of Innate Behavior: Courtship and Feeding
17:45 – 18:00 Break
18:00 - 20:00 Symposium 1
Neural Circuits and Behavior in Drosophila (Chair: Alexander Borst)
Ian Meinertzhagen (Canada)
Alexander Borst (Germany)
Michael Dickinson (USA)
Vivek Jayaraman (USA)
Wednesday
April 11 Morning
08:15 – 09:00 Keynote Lecture 2
Martin Schwab (Switzerland)
Structural Plasticity and Hardware Repair After CNS Injury
09:00 – 11:00 Symposium 2
Cortical Reorganisation following Brain Injury (Chairs: Mathias Bähr & Melanie Wilke)
Melanie Wilke (Germany) Reorganisation of spatial networks following reversible lesions in thalamo-cortical circuits: fMRI and single cell studies in monkeys
Christian Gerloff (Hamburg) Reorganisation of the motor network following irreversible brain lesions in stroke patients
Giacomo Koch (Italy) Hyperexcitability of parietal-motor functional connections in the intact left-hemisphere of patients with neglect: combined TMS and MRI studies in human patients
Andreas Luft (Switzerland) Neurophysiology-based approaches for neurorehabilitation
11:00 - 11:30 Coffee Break
11:30 - 13:30 Special Interest Session 1
Accumbens cholinergic interneurons as a therapeutic target in substance-use disorders: basic science (Chair: Gerald Zernig)
Ilka Diester and Karl Deisseroth (USA) Optogenetic control of accumbens cholinergic interneuron activity in cocaine reward
Louk Vanderschuren (The Netherlands) Local intra-accumbens stimulation of mu opioid receptors and social play: Role of cholinergic interneurons and GABAergic medium spiny neurons
Karine Guilleme (France) Feasibility of studying accumbens network activity with microelectrode arrays and of correlating electrophysiologic data with neurochemistry
Gerald Zernig (Austria) Possible differential role of accumbens cholinergic interneurons in drug- vs social interaction reward
Wednesday
April 11 Afternoon
16:00 – 16:45 Keynote Lecture 3
Edvard Moser (Norway)
Brain Maps for Space
16:45 – 17:15 Coffee Break
17:15 – 19:15 Symposium 3
Axonal Computation of Neurotransmitter Release (Chair: Dimitri Rusakov)
Beverly Clark (UK) Direct measurement of signalling in mammalian central axons
Dominique Debanne (France) Analog-digital signaling in hippocampal axons
Yuji Ikegaya (Japan) Functional and structural roles of axon cables in synaptic output
Nigel Emptage (UK) The role of glutamate autoreceptors in transmitter release
Thursday
April 12 Morning
08:15 – 09:00 Keynote Lecture 4
Anne-Marie Craig (Canada)
To be Announced
09:00 – 11:00 Symposium 4
Ubiquitin-Like Proteins in Nerve Cell Development and Synaptic Function and Plasticity (Chairs: Damian Refojo & Nils Brose)
Nils Brose (Germany) Nedd4-family ubiquitin ligases in nerve cell development and differentiation
Damian Refojo (Germany) Needing Neddylation: A role for Nedd8 in neuronal development
Andreas W. Püschel (Germany) Function and regulation of Rap1 GTPases during neuronal differentiation
Azad Bonni (USA) Regulation of neuronal connectivity by ubiquitin signaling
11:00 - 11:30 Coffee Break
11:30 - 13:30: Special Interest Session 2
Conditioned vulnerability elicited by metabolic insults occurring at birth: new paradigms for understanding neuropsychiatric disorders with delayed clinical onset
(Chair: Mario Herrera-Marschitz)
Peter J Gebicke-Haerter (Germany) System biology, epigenetics, and beyond: new paradigms and understandings on development of mental diseases.
Andre Fisher (Germany) Epigenetics in schizophrenia
R. Andrew Tasker (Canada) Repetitive insults facilitate disease progression and disease diversity
Mario Herrera-Marschitz (Chile) Asphyxia at birth increases the vulnerability to postnatal metabolic insults
Thursday
April 12 Afternoon
16:00 – 16:45 Keynote Lecture 5
Erin Schuman (Germany)
Local Protein Synthesis
16:45 – 17:15 Coffee Break
17:15 – 19:15 Symposium 5
The neurobiology of Sleep
(Chair: William Wisden)
Helmut Haas (Germany) Waking with the hypothalamus
Raphaelle Winsky-Sommerer (UK) Physiology and pharmacology of sleep: novel insights into the role of GABAergic and adenosinergic transmission
Giorgio F. Gilestro (UK) Clues to sleep’s function: sleep and learning in Drosophila
William Wisden (UK) Neuronal pathways of sleep and anaesthesia.
19:15 – 20:30 Poster Session
Friday
April 13 Morning
08:15 – 09:00 Keynote Lecture 6
Gilles Laurent (Germany)
To be Announced
09:00 – 11:00 Symposium 6
Stem Cells and Neurodegenerative Diseases (Chairs: Govindan Dayanithi and Eva Sykova)
Zaal Kokaia (Sweden): Stem cells and stroke
Eva Sykova (Czech Republic): Use of stem cells for treatment of neurodegerative diseases
Lawrence Rajendran (Switzerland): Cellular complexity underlying Alzheimer's Disease
Govindan Dayanithi (France): Calcium homeostasis in stem cells and neurodegeneration (Alzheimer's Disease and Amyotrophic Lateral Sclerosis)
Friday
April 13 Afternoon
16:00 – 16:45 Keynote Lecture 7
Idan Segev (Israel)
Inhibiting the Brain - Design Principles
16:45 – 17:15 Coffee Break
17:15 – 19:15 Symposium 7
Imaging neuron subcellular organization and activity; from molecules to function (Chair: Daniel Choquet)
Daniel Choquet (France) A nano-scale view into post synaptic membrane organization and function
Thomas Oertner (Germany) Synaptic plasticity: adjusting weights or changing topology?
Valentin Nägerl (France) Superresolution imaging of glianeuron interactions at synapses
Bernardo Sabatini (USA) Neuromodulatory control of striatal circuity in the mouse
Antoine Triller (France) The synapse as a statistical nanomachine
19:30 Gala Dinner (free for Central Spa hotel residents, others book at hotel front desk for 50,- €)
Saturday
April 14
08:15 – 10:15 Symposium 8
Neuroethology: Novel Approaches to Studying the Brain in Action (Chair: Georg Keller)
Florian Engert (USA) Whole-brain neural dynamics during rapid motor adaptation in larval zebrafish
Richard Hahnloser (Switzerland) Sensorimotor learning of birdsong without reinforcement
Michael Häusser (UK) Spatial navigation: the view from inside a single cell
Carl Petersen (Switzerland) Synaptic mechanisms of sensory perception
10:15 – 10:45 Coffee Break
10:45 – 12:45 Symposium 9
Neurogenesis and Glial function and dysfunction in aging and neurodegeneration: the ultimate neural symbiosis (Chair: Jose Julio Rodriguez Arellano)
Djoher Nora Abrous (France): Neurogenic changes in aging
Prof. José Julio Rodriguez Arellano (Spain) Neurogenic impairment and recovery in Alzheimer's disease: a concomitant process with glial alterations.
Alexei Verkhratsky (UK): Astroglial ionotropic receptors in neurodegeneration: gliotransmission vs. neurotransmission
Lydia Vargova (CZ): Changes in CNS diffusion parameters during aging and Alzheimer´s disease
12:45 End of meeting and departure