Organizing Committee
Tobias Bonhoeffer (Germany)
Nils Brose (Germany)
Alois Saria (chair, Austria)
Stephan Schwarzacher (Germany)
Final Program
Sunday
March 26 Afternoon
16:00 - 17:30 Registration
17:30 - 18:00 Welcome Cocktail
18:00 - 18:45 Keynote Lecture 1
ADI MIZRAHI (ISRAEL) TRAPing cortical plasticity in the mouse auditory system
Monday
March 27 Morning
08:15 -
09:00 Keynote Lecture 2
BETH STEVENS (USA) How are CNS Synapses Eliminated in Health and Disease
09:00 - 11:00 Symposium 1
From Genetic to Functional Cell-Type Diversity in the Cerebral Cortex
Chair: Simon
Hippenmeyer (Austria)
Speakers:
Simon Hippenmeyer (Austria)
Mechanisms Generating Cell-Type Diversity in the Cerebral Cortex
Denis Jabaudon (Switzerland)
Dynamic control of neuronal diversity in the
developing neocortex
Thomas Mrsic-Flogel (Switzerland)
A
single-cell anatomical blueprint for intracortical information transfer from
primary visual cortex
Laura Cancedda (Italy)
Cellular
microenvironment and cortical development
Monday
March 27 Afternoon
16:00 - 18:00 Symposium 2
Neuronal and Glial Microcircuits Controlling Breathing and Cardiorespiratory Integration
Chairs: Jan-Marino Ramirez (USA) & Stephan Schwarzacher (Germany)
Speakers:
Jack L. Feldman (USA)
Looking for inspiration
Kevin Yackle (USA)
Unraveling the neuronal subtypes of the inspiratory
Jan-Marino Ramirez (USA)
Excitatory microcircuits controlling inspiration and postinspiration
Gregory Funk (Canada)
The role of glia in the control of breathing
18:00 - 18:20 Coffee Break
18:20 - 20:20 Symposium 3
Nano-machinery of synapses: new insights
Chair: Dmitri Rusakov (UK)
Speakers:
Daniel Choquet (France)
Linking
AMPA receptor nanoscale organization and function at excitatory synapses
Simon Wiegert (Germany)
Optical quantal analysis
at the Schaffer collateral synapse
Valentin Nägerl (France)
Super-Resolution
Imaging of the Interstitial Fluid to Reveal the Nano-Anatomical Organization of
Live Brain Tissue
Dmitri Rusakov (UK)
Nanoscopic functional
identity of individual excitatory synapses in
situ
Tuesday
March 28 Morning
08:15 -
09:00 Keynote Lecture 3
TOM SüDHOF (USA) The molecular logic of neural circuits: Neurexins and beyond
09:00 - 11:00 Symposium 4
Neuroligin-dependent synaptic signaling
Chairs: Markus Missler & Nils Brose (Germany)
Speakers:
Katherine Roche (USA)
Activity-dependent
cleavage of neuroligin isoforms
Dilja Krüger (Germany)
Neuroligin 2 regulates anxiety behaviors
through effects on amygdala inhibitory synapses
Peter Jedlicka (Germany)
The role of neuroligins in the regulation of excitation and inhibition of the
dentate circuit in vivo and in silico
Olivier Thoumine (France)
Biophysical properties
of the neurexin-neuroligin trans-synaptic adhesion complex
Jürgen Klingauf (Germany)
Structure and function of presynaptic membrane domains studied in Xenapses-purely presynaptic boutons induced on Neurologin-micropatterned substrates
Tuesday
March 28 Afternoon
16:00 - 18:00 Symposium 5
Epigenetics and the brain
Chair: Gunter Schumann (UK)
Speakers:
Darina Czamara (Germany)
Effect of prenatal stress on the child’s epigenome
Sylvane
Desrivieres (UK)
Hunting for epigenetic markers of brain structure
Gunter Schumann (UK)
How does stress affect the adolescent brain?
Tomas J.
Ekström (Sweden)
An imprinted track in chronic alcoholism?
18:00 - 18:20 Coffee Break
18:20 – 20:20 Symposium 6
Cortical circuit formation: from stem cells to differentiated neurons.
Chair: Victor Tarabykin (Germany)
Speakers:
Federico Calegari (Germany)
Epigenetic
Control of Neural Stem Cells During Corticogenesis
Silvia Cappello (Germany)
Modeling cortical development and neuronal migration disorders in human
cerebral organoids
Ralf Stumm (Germany)
Chemokine-guided migration
of interneurons in the cerebral cortex
Victor Tarabykin (Germany)
Molecular control of cortical connectivity
Wednesday
March 29 Morning
08:15 -
09:00 Keynote Lecture 4
ELISABETH BINDER (GERMANY) Molecular mechanisms of gene x stress interactions,
implication for disease
09:00 - 11:00 Symposium 7
200 years Parkinson’s Disease: Genetics, Pathophysiology and Treatment
Chair: Jörg B. Schulz (Germany)
Speakers:
Mark Cookson (USA)
LRRK2 pathways: Relevance for inherited and sporadic Parkinson’s disease
Roberto Cappai (Australia)
Alpha-synuclein, mitochondria and dopamine – a Parkinson’s disease triumvirate
Björn Falkenburger (Germany)
Cellular events involved in clearance of alpha-synuclein aggregates
Mathias Bähr (Germany)
Neuroprotection in PD:
lost in translation?
11:00 - 11:20 Coffee Break
11:20 - 13:20 Special Interest Session 1
Neuroinflammation:
novel concepts and paths: from understanding to therapy“
Chair: Heinz Wiendl (Germany)
Speakers:
Frauke
Zipp (Germany)
Crosstalk of immune and nervous system
Johannes Vogt and Robert Nitsch (Germany)
Lipid signalling at central synapses – implications for neurological diseases
Sven Meuth (Germany)
Consequences of adaptive and innate inflammation on the neuronal network
level
Heinz Wiendl (Germany)
Molecular
cells as determinants of neuroinflammatory lesion development and topography
implications for treatment of neuroimmunological disorders
Wednesday
March 29 Afternoon
16:00 - 18:00 Special Interest Session 2
Mechanisms and Strategies of Neurorepair
Chair: Srecko Gajovic (Croatia)
Speakers:
Lars Klimaschewski (Austria)
Interference with Sprouty2/4 is neuroprotective and improves axonal regeneration
Pavla Jendelova (Czech Republic)
Neural progenitors derived from iPS cells in the treatment of CNS disorders
Pavle Andjus (Serbia)
Astrocytes as possible targets of repair in amyotrophic lateral sclerosis
Sarka Kubinova (Czech Republic)
Human umbilical cord derived mesenchymal stem cells and biomaterials in spinal cord repair
Srecko Gajovic (Croatia)
Neuroinflammation mediated by TLR2 modulates brain repair after ischemic injury
18:00 - 19:30 Coffee and Poster Session
19:30 Gala Dinner (free for Das Central hotel residents, others book at registration desk for 50,- € until Tuesday evening)
Thursday
March 30 Morning
08:15 - 09:00 Keynote Lecture 5
GERO MIESENBöCK (UK) Time to decide
9:00-11:00 Symposium 8
ISN Symposium on Autophagy in neurodegeneration: New insights underpinning therapy for neurological diseases.
Chairs: Olga Corti (France) and Philip Beart (Australia)
Speakers:
Philip Beart (Australia)
Autophagy
good and bad: Beneficial targeting in neuropathologies
Klas Blomgren (Sweden)
Neuroprotection
by selective neuronal deletion of Atg7 in neonatal brain injury
Angelo Poletti
(Italy)
Autophagy and polyglutamine diseases: The case for Spinal
and Bulbar Muscular Atrophy
Olga Corti (France)
Mechanisms
of mitochondrial quality control and consequence of their dysfunction in
autosomal recessive Parkinson’s disease
11:00-11:20 Coffee & End of the Meeting
Poster Session
Wednesday
March 29
18:00 - 19:30